Active Studies Finder

Overview

Are you interested in taking part in a research study that aims to reduce anxiety in older people with chronic worry? 

The purpose of this trial is to see if a new form of talking therapy called Acceptance and Commitment Therapy plus usual care can reduce anxiety in older people with chronic worry that has not improved after previous treatment compared to usual care alone.

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This study aims to find out whether an antidepressant medication (sertraline) can reduce the risk of depression happening at all after first-episode psychosis (FEP), and whether preventing depression can improve recovery.

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This study is no longer looking for new participants but is still ongoing.

This study seeks to understand the scale and nature of avoidable harm in prison healthcare.

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We want to find out if behavioural activation (BA) works for young people with low mood. There are a lot of keen therapists in Child and Adolescent Mental Health Services (CAMHS) who would like to give better help to young people but need more training. We would like to give these therapists training in our BA. We also want to find out if our BA is good value for money, how easy it is to use for young people, carers and clinicians, and if it can reduce long waits for other therapy.

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Overview

We are looking for people who may be at high risk of developing Bipolar Disorder (BD) to take part in a research trial looking at the possible benefits of Cognitive Behavioural Therapy (CBT) to help with difficulties associated with high and/or low mood.

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Overview

Breaking Free Online is an internet-based, computerised treatment programme which is designed to help people to understand what may be driving their drug or alcohol use. The programme is designed to help people to learn to use psychological techniques to help them cope and control their drug or alcohol use and make positive changes to their lifestyle and health.

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Overview

We are looking for healthy volunteers, people with memory problems, people with movement disorders and stroke survivors to help us with a new research study. 

This study is developing a new computer program to help improve the quality of care for people who may be experiencing changes to their thinking and memory

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CONNECT is a study using digital technology to see if we can detect in advance if someone’s mental health might be getting worse.

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EDGI is a project set up to explore genetic and environmental risk factors in individuals who have experienced or been diagnosed with an eating disorder. We want to understand how genetic and environmental risk factors influence eating disorders.

Together, with your contribution, we can make a difference and improve future treatments! 

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Overview

This study is no longer looking for new participants but is still ongoing. 

This study aims to find out how Alcohol Assertive Outreach Teams (AAOT) services were first set up and how well they run. For this purpose, two experienced researchers will interview service users, staff, and other key people about their experiences with AAOT. 

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The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Our aim is to collect the psychological, medical, and genetic information of 40,000 people with experience of anxiety and depression.

We also want to recruit 10,000 individuals without any history of mental disorder to help us explore why some people do and some people don’t become ill. This will help us to better understand the role both our genes and environment play in the development of these illnesses. 

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The goal of the IPPACT project is to improve the detection of individuals with At Risk Mental States (ARMS) most at risk of transitioning to first episode psychosis.

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Combining stop smoking support with online mental health treatment via SilverCloud+.

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We want to work with service users, carers, and professionals to develop a support package to help adult service users to manage the hunger side-effects of antipsychotic medication. 

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We want to find out if parents with psychosis are happy to use a self-help parenting programme, and if they find it helpful and easy to use. 

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The reason for this research is that we do not know what is the optimum time that people should remain in Early Intervention services. This study is part of a larger programme of work which will help the research team make suggestions for the optimum time for the duration of Early Intervention services. 

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The purpose of this study is to see if genetic testing could be useful for patients who are currently taking or due to start taking an antidepressant, antipsychotic or mood stabilising medicine as treatment for a mental illness. We also seek to understand how genetic and environmental factors may lead to the onset of mental health problems.

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Overview

There is some evidence that some cases of psychosis may be caused by a specific problem with the immune system. The immune system normally controls our ability to fight infection. If the immune system goes wrong it may cause condition called ‘autoimmune’ diseases. We can diagnose some of these diseases using blood tests.

This study aims to see how many people with psychosis may have this specific problem with their immune system. We can find out that by testing your blood sample for specific antibodies. 

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Overview

We have developed the PROSPECT programme for people in prison who may be at risk of suicide. The aim of the programme is to help prevent suicide in prisons. We are currently conducting research to find out if the PROSPECT programme is effective. 

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RAPID is a study using online and phone-based psychological support to help prevent psychiatric hospital admissions for those with suicidal thoughts. The RAPID trial aims to compare two remote interventions with the standard care people usually receive to find out how best to help those who experience suicidal thoughts, and if this can reduce admissions to hospital.

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Overview

This study is no longer looking for new participants but is still ongoing.

People with mental health conditions have higher risks of cardiovascular and metabolic diseases compared to the general population. Individuals can reduce their risk adopting healthier lifestyles, for instance increase their physical activity. Digital technologies (such as Zoom) can be used to deliver remote exercise intervention. However, there is currently little understanding of how this might work best in mental healthcare. 

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The Staff TIME project aims to find out what is helpful or unhelpful when seeking support by carrying out interviews with members of staff. This will help us collect information about your experiences on acute inpatient wards and with staff support, and any suggestions you may have to improve staff support.

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StrataStem Ltd specialises in the cell biology of Alzheimer’s disease and is looking at new methods of early diagnosis and in identifying new drugs to treat the disease. The aim of the study is to create new neurons (brain cells). This will then allow us to study the genes involved in dementia. The overall aim of the research is to help us understand the biology behind Alzheimer’s disease and, potentially, identify new drugs to treat the disease.

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Talking With Voices (TwV) is a new form of therapy that comes from the work of the International Hearing Voices Movement. It is based on the idea that what voices say may reflect real-life conflicts and difficulties in the life of the voice hearer. 

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The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

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We are conducting a new clinical trial to see if it would be useful to offer Eye Movement Desensitisation and Reprocessing (EMDR) and Trauma Focussed Cognitive Behavioural Therapy (TF-CBT), for people who have experienced distressing life events and psychological difficulties. 

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We want to explore if matching certain subgroups of people with depression to a particular therapy would help patients.  In this pilot randomized controlled trial, we will randomly assign some Talking Therapies sites to an experimental group, and others to a control group.  The TherapyMatch-D computer programme will give a personalised treatment recommendation to some patients in the experimental group. 

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The AMICABLE study will evaluate a Peer-led Problem Support Mentoring Scheme. The project expands on pilot work conducted in two prisons. It will identify whether it can demonstrate a scalable and sustainable intervention to support the mental health of people in custody across the wider prison estate using a six-step problem solving model.

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Overview

The study aims to assess the effectiveness of NHS and independent sector inpatient mental health rehabilitation services.

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This study is no longer looking for new participants but is still ongoing.

We are carrying out a clinical trial of a talking therapy called Method of Levels for people using Early Intervention in Psychosis services. The therapy will be delivered by care coordinators who are working in Early Intervention in Psychosis services. We think that training care coordinators in Method of Levels therapy could make Early Intervention in Psychosis services more helpful for people using them.

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